图表内容
STAR*D研究抑郁症患者治疗流程图HRSD≤7
Enrolled
7<HRSD<14
N=4
041)
N=508)
Missing HRSD
Citalopram
N=324)
N=3
110)
Exit
Follow-up
(N=1
074)
N=902)
Bupropion
Sertraline
Venlafaxine
Citalopram
Citalopram
Citalopram
Cognitive
SR
N=198)
XR
plus
plus
plus
therapy
N=190)
(N=192)
bupropion
buspirone
cognitive
N=40)
Level 2
SR
(N=225)
therapy
N-216
N=73)
Exit
Follow-up
Exit
Follow-up
(N=370)
(N=354)
N=33)
Nortriptyline
Mirtazapine
Lithium aug-
Ts aug-
Bupropion
Venlafaxine
(N=92)
mentation
mentation
Level
SR
XR
N=58)
N=53)
N=12)
Level 2A
Exit
Follow-up
Exit
Follow-up
N=143)
(N=64)
(N=7)
N=5)
Venlafaxine
Nortriptyl-
Mirtazapi-
Lithium
T;aug-
mine
XR plus
ine
ne
aug-
mentation
(N=43)
mirtazapine
N-3)
mentation
N=3)
Level3
N=47)
N=6
Follow-up
Exit
Follow-up
N=34
N=4)
Venlafaxine XR
N=3)
plus mirtazapine
(What are the treatment remission
response and extent of improvement rates after up to four trials of
essant therapies in real-world depressed patients?A reanalysis of the STAR*D study's patient-level data wi